Scientists at the Chinese Academy of Sciences have made progress in the research of multi-frequency ultrasound endoscopy

Release time:

2025-03-12 09:38

Ultrasound imaging is one of the mainstream imaging diagnostic methods and plays an important role in clinical practice. The ultrasound transducer is a key component of the ultrasound imaging system, and its center frequency determines the resolution of the ultrasound image. The higher the frequency, the easier it is to obtain a high-quality image; however, increasing the frequency often leads to a decrease in detection depth, limiting the imaging range of the transducer and hindering clinical use. Currently, the operating frequency of common ultrasound transducers is 2~20MHz, generally operating at a single frequency. If it is necessary to change the operating frequency to obtain the corresponding imaging effect, another probe must be replaced, which brings many inconveniences, especially in interventional ultrasound examinations (such as intravascular ultrasound), where changing the probe will greatly increase the patient's pain. This contradiction between resolution and imaging depth limits further improvement in the performance of ultrasound probes. How to make ultrasound images balance imaging resolution and imaging depth and improve imaging quality has become a problem that urgently needs to be solved.

　　Multi-frequency ultrasound imaging technology is expected to solve this contradiction. A multi-frequency ultrasound transducer can operate at different center frequencies and switch flexibly. When operating under low-frequency conditions, it can obtain a large detection depth and obtain "rough" information from a large area. After discovering "suspicious" areas, it switches to high-frequency working conditions to obtain detailed pathological information. After using image fusion technology, ultrasound images corresponding to different frequencies can be fused to obtain higher-quality images. Multi-frequency ultrasound transducers can significantly enrich the information of ultrasound images and improve the diagnostic range, which is an important development direction for ultrasound transducers.

　　Recently, a team of scientists from the Chinese Academy of Sciences—the Medical Acoustics Laboratory of the Suzhou Institute of Biomedical Engineering and Technology, with the support of cooperative enterprises, has developed a multi-frequency, large-bandwidth ultrasound probe based on piezoelectric composite materials, building on its existing single-frequency ultrasound probe development technology. This probe can work collaboratively (synchronously or asynchronously; synchronously means that several frequencies work simultaneously, asynchronously means that several frequencies work at different times) at three different operating frequencies: 12MHz, 20MHz, and 30MHz. After performing functions such as fusion of images of different frequencies and harmonic imaging, it can enrich ultrasound image information and imaging modes, achieving "one probe, multiple operating frequencies." This solves the problem of the inability to balance resolution and imaging depth, meeting the needs of various ultrasound detection, diagnosis, and interventional surgery, and improving the level of ultrasound medical equipment research and development and the diagnosis and treatment of related diseases.

　　Relevant research results areA triple-frequency transducer for endoscopic imaging: Simulation design and experimental verificationpublished online inSensors and Actuators A: PhysicalThe research work was supported by the National Natural Science Foundation of China, the Jiangsu Provincial Social Development-Clinical Frontier Technology Project, and the Youth Innovation Promotion Association of the Chinese Academy of Sciences.

Figure 1. Self-made multi-frequency ultrasound endoscope sample

Figure 2. Multi-layer phantom ultrasound images obtained by the multi-frequency ultrasound endoscope

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